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Orange juice has many potential positive effects when it comes to cancer, particularly because it is high in antioxidants from flavonoids such as hesperitin and naringinin, the indianexpress.com reported.

Biological effects of orange juice in vitro are largely influenced by the juice's composition, which is dependent on physiological conditions of the oranges such as climate, soil, fruit maturation, and storage methods post-harvest.

The review article, published in the journal Nutrition and Cancer, summarises several biological effects of orange juice that can contribute to chemo-prevention, including antioxidant, antimutagenic and antigenotoxic, cytoprotective, hormonal, and cell signalling modulating effects.

Orange juice has antimicrobial and antiviral action and modulates the absorption of xenobiotics, researchers said.
Excessive drinking of orange juice for individuals from these groups has the potential to create noxious effects, hyperkalemia, and has been associated with both food allergies and bacterial outbreaks in cases where the juice was unpasteurised.