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U.S. health officials on Friday confirmed the first case of an American infected with a mysterious Middle East virus. The man fell ill after arriving in the U.S. about a week ago from Saudi Arabia where he is a health care worker, The Associated Press reported.

The man is hospitalized in Indiana with Middle East respiratory syndrome, or MERS, according to the Centers for Disease Control and Prevention, which is investigating the case along with Indiana health officials.

Saudi Arabia has been the center of an outbreak of MERS that began about two years ago. At least 400 people have had the respiratory illness, and more than 100 people have died. All had ties to the Middle East or to people who traveled there. Infections have been previously reported among health care workers.

MERS belongs to the coronavirus family that includes the common cold and SARS, or severe acute respiratory syndrome, which caused some 800 deaths globally in 2003.

The MERS virus has been found in camels, but officials don't know how it is spreading to humans. It can spread from person to person, but officials believe that happens only after close contact. Not all those exposed to the virus become ill.

But it appears to be unusually lethal — by some estimates, it has killed nearly a third of the people it sickened. That's a far higher percentage than seasonal flu or other routine infections. But it is not as contagious as flu, measles or other diseases. There is no vaccine or cure for MERS.

The CDC on Friday released only limited information about the U.S. case: The man flew to the United States about a week ago, with a stop in London. He landed in Chicago and took a bus to the neighboring state of Indiana. He didn't become sick until arriving in Indiana, the CDC said. Symptoms include fever, cough, breathing problems, which can lead to pneumonia and kidney failure.

CDC officials say they are sending a team to investigate the man's illness, his travel history and to track down people he may have been in close contact with.