Health 17:09 30/10/2014

Ebola’s family tree: Disease may have existed for 23 million years

A family of viruses that Ebola belongs to may have existed over 20 million years ago, according to a new study published in the journal PeerJ, Medical Daily reports.

Researchers from the University of Buffalo found that Filoviruses did not begin appearing 10,000 years ago as previously thought, but in fact have been around for much longer. The Ebola virus belongs to the family of filoviruses, also known as the Filoviridae family. “Filoviruses are far more ancient than previously thought,” said Derek Taylor, lead author of the study and a professor of biological sciences at the University of Buffalo, in the press release. “These things have been interacting with mammals for a long time, several million years.”

Despite the fact that scientists around the world are frantically searching for a cure and better treatment for Ebola, there’s still much to learn about the deadly virus. The authors of the study argue that better understanding Ebola’s evolutionary roots could “affect design of vaccines and programs that identify emerging pathogens.”

The study focused not on Ebola specifically, but the ancestors and family of Ebola to better understand where it may have come from. Both the Ebola virus and Marburg virus — also a hemorrhagic fever virus that belongs to the Filoviridae family — were found to be tied to ancient evolutionary lines, and they shared a common ancestor 16 to 23 million years ago. The authors discovered this by examining viral fossil genes, which are bits of genetic material that animals acquire from viruses during infection. They found Filovirus-like genes in rodents, particularly hamsters and voles, which means that the filovirus family is likely as old as these rodents' common ancestor. The genetic material in these fossils were more closely related to Ebola than Marburg, meaning the two lines had already begun to diverge during the Miocene Epoch, a time period that occurred five to 23 million years ago. During this time, there were also warmer climates, as well as the first appearances of kelp forests and grasslands on Earth.

“These rodents have billions of base pairs in their genomes, so the odds of a viral gene inserting itself at the same position in different species at different times are very small,” Taylor said. “It’s likely that the insertion was present in the common ancestor of these rodents.”

The Filoviridae family is defined by viruses that form virions, or filamentous infectious viral particles. The Ebola virus and Marburg virus are the most well-known among this group, and they are both severe viruses that cause hemorrhagic fevers in both animals and humans (essentially, they're deadly diseases that lead to fever and bleeding).

Taylor believes that the study may help in the fight against Ebola by widening our knowledge about its history, and identifying what species are most likely to be hosts of the virus. “When they first started looking for reservoirs for Ebola, they were crashing through the rainforest, looking at everything — mammals, insects, other organisms,” Taylor said. “The more we know about the evolution of filovirus-host interactions, the more we can learn about who the players might be in the system.” 



Source Panorama.am
Share |
Տեքստում սխալ կամ վրիպակ նկատելու դեպքում, ուղարկեք խմբագրին հաղորդագրություն` նշելով տվյալ սխալը, այնուհետև սեղմելով Ctrl-Enter:

Newsfeed

17:03
Temperatures to drop further across Armenia
Scattered rain is expected in Armenia’s regions on Friday, Saturday and next week. Foggy conditions are possible in some parts of the...
16:30
Khachanov makes it to second round of China Open
Russian-Armenian Karen Khachanov, the No 7 seed, won against Spanish lucky loser Roberto Carballes Baena 6-4, 6-4 to move into the second round...
16:06
Opposition MP blames Pashinyan's government for 2020 war defeat
Opposition deputy Tigran Abrahamyan accused Prime Minister Nikol Pashinyan's government of deliberately leading the country to defeat in the...
15:36
‘National disgrace': Opposition leader slams Pashinyan's meeting with Erdogan in New York
Seyran Ohanyan, the leader of the opposition Hayastan faction in the Armenian parliament, said opposition forces were striving to prevent the...
15:05
NSW MPs call on Australians to boycott COP29
Three members of the New South Wales Parliament have delivered powerful addresses on the floor of the Legislative Assembly to mark the first...
14:32
Archbishop Sahak Mashalyan arrives at Mother See
Archbishop Sahak Mashalyan, Armenian Patriarch of Constantinople, on Friday arrived at the Mother See of Holy Echmiadzin, the Armenian church...
14:04
Artsakh president commemorates 2020 war anniversary
Artsakh President Samvel Shahramanyan on Friday visited the Yerablur Military Pantheon in Yerevan to pay tribute to fallen soldiers on the...
13:30
Alen Simonyan to reportedly attend re-consecration of Echmiadzin cathedral
Armenian National Assembly Speaker Alen Simonyan will attend the re-consecration ceremony of the Mother Cathedral in Etchmiadzin on Sunday,...
13:03
No decision yet on next stage of Armenian-Azeri border delimitation, official says
No decision has yet been made on the next stage of the Armenian-Azerbaijani border delimitation process, Armenian Deputy Prime Minister Mher...
12:34
Ruben Vardanyan, other Armenian leaders mark one year as political prisoners in Azerbaijan
Today marks the first anniversary of the arbitrary arrest by Azerbaijani authorities of eight Armenian leaders, commencing with the arrest of...
12:15
Ex-defense minister set to become Japan's next PM
After five tries, former Defense Minister Shigeru Ishiba will finally lead the Liberal Democratic Party — and Japan, The Japan Times...
12:03
Pashinyan at UN: Armenian proverb says, 'Let us speak the positive in order to be well'
As part of his working visit to New York, Armenian Prime Minister Nikol Pashinyan on Thursday delivered a speech at the 79th session...
11:36
Armenian deputy PM acknowledges problems in relations with Russia
Armenian Deputy Prime Minister Mher Grigoryan acknowledged problems in relations with Russia and other countries. "We need to make...
11:15
Artsakh president pays tribute to fallen soldiers on war anniversary
Artsakh President Samvel Shahramyan on Friday visited the Yrablur Military Pantheon in Yerevan to pay homage to fallen soldiers on the...
11:00
Armenia, Azerbaijan agree to put additional efforts towards signing of peace deal
On September 26, under the initiative and with participation of U.S. Secretary of State Antony Blinken, Armenian Foreign Minister Ararat...
17:15
Wheat production in Armenia unprofitable, economy minister says
Wheat production in Armenia is economically unprofitable, Minister of Economy Gevorg Papoyan told reporters outside the Armenian government...
16:46
Martin Scorsese's two film projects postponed
Martin Scorsese, the Oscar-winning filmmaker behind some of cinema’s most iconic works, had planned to begin shooting two highly...
16:34
Yerevan to host Meghraton exhibition and sale of bee products
Meghraton exhibition and sale of honey and other bee products is set to take place at Yerevan's Yeraz Park on September 28-29. The event is...
16:17
Political analyst slams Pashinian's UN speech, photo with Erdogan
Political analyst Suren Surenyants hit out at Prime Minister Nikol Pashinyan for his speech at the Summit of the Future held on the sidelines of...
15:35
UNICEF and Germany to scale up child protection services for refugee children in Armenia
UNICEF and the German Embassy in Yerevan announced a new contribution of 2,9 million Euros from the German Federal Foreign Office in the...
15:05
New COVID strain cases detected in Russia
Specialists from the Russian Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing have recorded two coronavirus...
14:35
Armenian Airlines to launch direct flights between Yerevan, Volgograd
Armenian Airlines will launch direct flights between Yerevan and Volgograd, a city in southwest Russia, starting from 1 December 2024....
14:07
Political analyst says South Caucasus turning into a 'powder keg'
Political analyst Sergei Melkonian, a research fellow at the Applied Policy Research Institute (APRI Armenia), warns that the South Caucasus...
13:45
Today marks Komitas' 155th anniversary
September 26 marks the 155th birth anniversary of Komitas Vardapet, a prominent Armenian composer, priest, musicologist, arranger, singer and...
13:30
Georgia seeks to transform South Caucasus into a region of opportunities, PM says
Georgia has led the effort to transform the South Caucasus into a region of opportunities, Georgian Prime Minister Irakli...
12:55
Pashinyan's wife chats with Turkish first lady in New York
Armenian Prime Minister Nikol Pashinyan's spouse, Anna Hakobyan, on Wednesday attended a reception in New York hosted by U.S. First Lady...
12:30
U.S. government announces $20,600,000 support to Armenia
Secretary of State Blinken and USAID Administrator Power spotlight democratic progress in Armenia and announce $20,600,000 from the United...
12:17
Blinken to meet with Armenian, Azeri FMs on Thursday evening
U.S. Secretary of State Antony Blinken’s meeting with Armenian Foreign Minister Ararat Mirzoyan and Azerbaijani Foreign Minister Jeyhun...
11:55
The government has decided to remove Mikayel Minasyan's brother from his position as minister, continuing its repressive measures
For three days, members of Armenia's ruling "Civil Contract" faction have been collecting signatures to dismiss Justice Minister...
11:35
Iran warns Israel against 'full-scale war' in Lebanon
Israel's leaders must understand their crimes won't go unpunished, Iran's foreign minister has said on the sidelines of the UN....

Follow us and get updates!

Most popular articles

{"core.blocks.header.spell_message1":"Selected mistake: ","core.blocks.header.spell_message2":"Send a message about the mistake?"}