Health 16:37 05/11/2014

Another reason to quit cigarettes: Secondhand smoke makes people around you fat

Some people swear smoking cigarettes keeps them slim.

But being exposed to cigarette smoke can actually make people pile on the pounds - the surprise is that secondhand smoke is the biggest culprit, the Daily Mail reports.

Innocent victims of secondhand cigarette smoke are the most likely to gain weight, researchers found.

'For people who are in a home with a smoker, particularly children, the increased risk of cardiovascular or metabolic problems is massive,' said lead author Professor Benjamin Bikman, of Brigham Young University in Utah.

Passive smoking damages the body because second-hand smoke contains more than 4,000 chemicals, many of which are irritants and toxins, and some of which are known to cause cancer.

Data shows half of the U.S. population is exposed at least once daily to secondhand cigarette smoke and approximately 20 per cent of young children live with someone who smokes in the home.

In the UK it's estimated that second-hand smoke kills over 12,000 people every year from lung cancer, heart disease, stroke and the lung disease Chronic Obstructive Pulmonary Disease (COPD).

Professor Bikman, and his co-author Professor Paul Reynolds wanted to investigate how cigarette smoke is tied to metabolism.

They wanted to pinpoint the mechanism behind why smokers become insulin resistant, which leads to weight gain.

To carry out their study, they exposed mice to or second-hand smoke and analysed their metabolic progression.

Sure enough, those exposed to smoke put on weight.

When they drilled down to the cellular level, they found the smoke triggered a tiny lipid called ceramide to alter mitochondria in the cells, causing disruption to normal cell function and inhibiting the cells' ability to respond to insulin.

The lungs provide a vast interface with the environment, and the research shows that passive smoking alters a body's sensitivity to insulin, Professor Reynolds said.

'Once someone becomes insulin resistant, their body needs more insulin. And any time you have insulin go up, you have fat being made in the body.'

The key to reversing the effects of cigarette smoke, they discovered, is to inhibit ceramide.

The researchers found the mice treated with myriocin - a known ceramide blocker - didn't gain weight or experience metabolic problems, regardless of their exposure to the smoke.

However, when the mice exposed to smoke were also fed a high-sugar diet, the metabolic disruption could not be fixed.

Now Professor Bikman and his team are in a race with other researchers to find a ceramide inhibitor that is safe for humans.

'The idea that there might be some therapy we could give to innocent bystanders to help protect them from the consequences of being raised in a home with a smoker is quite gratifying,' he said.

But for the smokers themselves, there is no 'protective therapy' available.

'They just have to quit,' he said. 'Perhaps our research can provide added motivation as they learn about the additional harmful effects to loved ones.' 



Source Panorama.am
Share |
Տեքստում սխալ կամ վրիպակ նկատելու դեպքում, ուղարկեք խմբագրին հաղորդագրություն` նշելով տվյալ սխալը, այնուհետև սեղմելով Ctrl-Enter:

Newsfeed

17:00
Armenian church honors St Gregory the Thaumaturgus and others
The Armenian Apostolic Church on Saturday commemorates St Gregory the Thaumaturgus, Nicholas the Bishop and St Myron the Wonderworker....
16:30
Banner at Armenian church in Watertown vandalized, police say
A banner at St. Stephen’s Armenian Church in Watertown has been vandalized, Watertown News reports, citing local police. The...
16:02
At least 3 arrested as Montreal anti-NATO protests turns violent
Montreal police say at least three people were arrested after protests turned violent Friday evening, with demonstrators throwing objects at...
15:45
Expert: Armenia pinned hopes on 'European fairy tales' and became isolated
Arthur Khachikyan, an international relations expert from Stanford University, claims the Armenian government’s poor foreign...
15:07
Armenian-Russian relations 'in agony', expert says
Hayk Khalatyan, a political analyst at the Verelq Information and Analytical Center, on Saturday accused Prime Minister Nikol Pashinyan and his...
14:32
Powerful Israeli airstrike kills 11 people in central Beirut
A powerful airstrike killed 11 people in central Beirut on Saturday, the Lebanese civil defence said, shaking the capital as Israel pressed its...
14:15
Expert: Armenian-Azeri talks somewhat stalled
Political analyst Suren Sargsyan claims the Armenian-Azerbaijani peace talks have somewhat stalled amid the change of government in the United...
13:33
Temperatures set to plunge next week
Clear weather is expected in Armenia's regions over the weekend. Rain and snow are forecast for most parts of the country next week....
13:06
Magnitude 4․3 quake hits Azerbaijan, felt in Armenia
A magnitude 4․3 earthquake struck Azerbaijan on Saturday afternoon. The quake was recorded 42 km northeast of the town of Goris in...
12:35
Opposition MP slams Pashinyan's Western Armenia remarks
Opposition Hayastan faction MP Levon Kocharyan has blasted Prime Minister Nikol Pashinyan's remarks on Western Armenia and Baku’s fake...
12:00
MP Hovik Aghazaryan says decided on his parliament seat
MP Hovik Aghazaryan of Armenia’s ruling Civil Contract party has made a decision on his parliament seat. The deputy has told the media...
11:36
US lawmakers request classified briefing on Turkey’s ties to Hamas
More than three dozen Democratic and Republican lawmakers are calling on the Biden administration to offer a classified briefing on...
11:15
Armenia's Mushegh Mkrtchyan wins bronze at World Military Wrestling Championships
Armenian serviceman Mushegh Mkrtchyan (92 kg) has clinched a bronze medal at the 37th CISM World Military Wrestling Championships in Yerevan,...
11:00
Switzerland bans exports to Polish firm after Swiss-made ammunition ends up in Ukraine
The Swiss government said Friday it is barring exports to a Polish military hardware supplier after concluding that some 645,000 rounds of...
17:12
Armenia to face Georgia in Nations League play-off
The 2024/25 UEFA Nations League knockout stage and play-off ties have been confirmed following the draw in Nyon, Switzerland on Friday....
16:36
Hayk Marutyan agrees to debate with Tigran Avinyan
New Power party leader Hayk Marutyan has agreed to a TV debate with incumbent Yerevan Mayor Tigran Avinyan. Marutyan, a former Yerevan...
15:45
Opposition politician: Pashinyan leading Armenia to 'final collapse'
Prime Minister Nikol Pashinyan’s administration is leading Armenia to the “final collapse” and Turkification, opposition...
15:05
Caretaker deputy justice minister sacked
Armenian Prime Minister Nikol Pashinyan has signed a decree to dismiss Armenuhi Harutyunyan as Acting Deputy Minister of Justice....
14:35
Armenian parliament speaker confirms MP's resignation
National Assembly Speaker Alen Simonyan has issued a statement on the resignation of Narek Zeynalyan as an MP from Armenia’s ruling Civil...
14:06
Visa restricts media access to key event in Yerevan
Visa has restricted the media access to the Cashless Forum 2024 to be held in Yerevan for the first time on November 22. Only...
13:36
Orban says he will invite Netanyahu to Hungary after ICC warrant
Prime Minister Viktor Orban said on Friday he would invite Israeli Prime Minister Benjamin Netanyahu to visit Hungary, saying he would guarantee...
13:11
Temps to plummet in Armenia
Clear weather is expected in Armenia's regions on Friday and over the weekend. Rain and snow are forecast for most parts of the country...
12:32
Alexis Ohanian showcases rare Armenian coin
Reddit co-founder Alexis Ohanian has showcased a rare Armenian coin from 95 BC featuring Tigranes the Great, a famous Armenian king....
12:16
German foreign minister criticizes Azerbaijan's human rights record
German Foreign Minister Annalena Baerbock criticized the human rights record of Azerbaijan during her first appearance at the UN Climate Change...
12:06
Minister shares new images captured by Armenia's first satellite
Armenia's Minister of High-Tech Industry Mkhitar Hayrapetyan has shared new satellite images from orbit captured by ARMSAT-1,...
11:36
World Cadet Chess Championship passes its halfway mark
The 2024 World Cadet Chess Championship has passed its halfway mark in Montesilvano, Italy. After 6 rounds, in the Open 12 category CM...
11:15
Iran to launch 'new and advanced centrifuges' in response to IAEA censure
Iran said Friday it would launch a series of "new and advanced" centrifuges in response to a resolution adopted by the IAEA that...
11:00
Armenian, Iranian foreign ministers hold phone call
Armenian Foreign Minister Ararat Mirzoyan on Thursday had a telephone conversation with his Iranian counterpart Seyed Abbas Araghchi....
17:07
Winter military draft starts in Armenia on November 25
The winter conscription for compulsory military service starts in Armenia on November 25 to run through January 31, 2025. The...
16:45
Russian spokeswoman told not to comment on ballistic missile strike live on air
Russia's foreign ministry spokeswoman Maria Zakharova received a phone call during a live press briefing on Thursday telling her not to...

Follow us and get updates!

Most popular articles

{"core.blocks.header.spell_message1":"Selected mistake: ","core.blocks.header.spell_message2":"Send a message about the mistake?"}