Health 18:50 28/01/2015

Scientists ask if Ebola immunizes as well as kills

A recent sharp drop in new Ebola infections in West Africa is prompting scientists to wonder whether the virus may be silently immunizing some people at the same time as brutally killing their neighbors, Reuters reports.

So-called "asymptomatic" Ebola cases - in which someone is exposed to the virus, develops antibodies, but doesn't get sick or suffer symptoms - are hotly disputed among scientists, with some saying their existence is little more than a pipe dream.

Yet if, as some studies suggest, such cases do occur in epidemics of the deadly disease, they may be a key factor in ending outbreaks more swiftly by giving secret protection to those lucky enough to be able to bat the infection away.

"We wonder whether 'herd immunity' is secretly coming up - when you get a critical mass of people who are protected, because if they are asymptomatic they are then immune," Philippe Maughan, senior operations administrator for the humanitarian branch of the European Commission, told Reuters. "The virus may be bumping into people it can't infect any more."

Latest World Health Organization data show new cases of infection in West Africa's unprecedented Ebola epidemic dropping dramatically in Guinea, Sierra Leone and particularly in Liberia.

Most experts are sure the main driver is better control measures reducing direct contact with contagious patients and corpses, but there may also be other factors at work.

So-called herd immunity is a feature of many infectious diseases and can, in some cases, dampen an outbreak if enough people get asymptomatic, or "sub-clinical" cases and acquire protective antibodies. After a while, the virus - be it flu, measles, polio - can't find non-immune people to be its hosts.

But some specialists with wide experience of disease outbreaks are highly skeptical about whether this phenomenon happens in Ebola, or whether it could affect an epidemic.

"There is some suggestion there may be cases that are less severe... and there may even be some that are asymptomatic," said David Heymann, an infectious disease expert and head of global health security at Chatham House.

"But herd immunity is just the wrong term. There could be household immunity developing, but even that is only hypothesis."

Others are more hopeful and are urging researchers in West Africa to seek out and test possible asymptomatic cases with a view to using the secrets of their silent immunity.

Steve Bellan of the University of Texas in the United States argues that if scientists can reliably identify asymptomatic people, they could help with disease-control tasks like caring for patients and conducting burials, reducing the number of non-immune people exposed in these risky jobs.

Bellan points to two studies in particular. One, conducted after an Ebola outbreak in Gabon in 1997, found that 71 percent of "seropositive" people - those with traces of the Ebola virus in their blood - did not have the disease. The other, published in April 2002, found 46 percent of asymptomatic close contacts of patients with Ebola were seropositive.

With the largest Ebola epidemic on record raging through three of Africa's most under-resourced countries, scientists and medics have, understandably, focused all efforts on the sick and dying and not on testing people with no symptoms.

If they do, however, and if they were to find what Bellan and some others suspect, it could prompt a reappraisal of what jolted a relatively sudden downturn in new cases.

Some researchers say they have identified a few cases in the current outbreak with mild symptoms and low concentrations of Ebola virus in the blood. One was a Guinean student who traveled to Senegal and is not known to have infected anyone else, despite having contact with dozens of people.

Ian MacKay, a virologist at Australia's University of Queensland, agrees that possible sub-clinically-acquired immunity is one of many unexplored mysteries of the Ebola virus.

"One thing that this particular outbreak shows is that we really don't know an awful lot about these kinds of infectious diseases," he said. "We tend to think we can answer all the questions, but this is one of those things we may end up being taught by the virus itself." 



Source Panorama.am
Share |
Տեքստում սխալ կամ վրիպակ նկատելու դեպքում, ուղարկեք խմբագրին հաղորդագրություն` նշելով տվյալ սխալը, այնուհետև սեղմելով Ctrl-Enter:

Newsfeed

15:05
NSW MPs call on Australians to boycott COP29
Three members of the New South Wales Parliament have delivered powerful addresses on the floor of the Legislative Assembly to mark the first...
14:32
Archbishop Sahak Mashalyan arrives at Mother See
Archbishop Sahak Mashalyan, Armenian Patriarch of Constantinople, on Friday arrived at the Mother See of Holy Echmiadzin, the Armenian church...
14:04
Artsakh president commemorates 2020 war anniversary
Artsakh President Samvel Shahramanyan on Friday visited the Yerablur Military Pantheon in Yerevan to pay tribute to fallen soldiers on the...
13:30
Alen Simonyan to reportedly attend re-consecration of Echmiadzin cathedral
Armenian National Assembly Speaker Alen Simonyan will attend the re-consecration ceremony of the Mother Cathedral in Etchmiadzin on Sunday,...
13:03
No decision yet on next stage of Armenian-Azeri border delimitation, official says
No decision has yet been made on the next stage of the Armenian-Azerbaijani border delimitation process, Armenian Deputy Prime Minister Mher...
12:34
Ruben Vardanyan, other Armenian leaders mark one year as political prisoners in Azerbaijan
Today marks the first anniversary of the arbitrary arrest by Azerbaijani authorities of eight Armenian leaders, commencing with the arrest of...
12:15
Ex-defense minister set to become Japan's next PM
After five tries, former Defense Minister Shigeru Ishiba will finally lead the Liberal Democratic Party — and Japan, The Japan Times...
12:03
Pashinyan at UN: Armenian proverb says, 'Let us speak the positive in order to be well'
As part of his working visit to New York, Armenian Prime Minister Nikol Pashinyan on Thursday delivered a speech at the 79th session...
11:36
Armenian deputy PM acknowledges problems in relations with Russia
Armenian Deputy Prime Minister Mher Grigoryan acknowledged existing problems in relations with Russia and other countries. "We need...
11:15
Artsakh president pays tribute to fallen soldiers on war anniversary
Artsakh President Samvel Shahramyan on Friday visited the Yrablur Military Pantheon in Yerevan to pay homage to fallen soldiers on the...
11:00
Armenia, Azerbaijan agree to put additional efforts towards signing of peace deal
On September 26, under the initiative and with participation of U.S. Secretary of State Antony Blinken, Armenian Foreign Minister Ararat...
17:15
Wheat production in Armenia unprofitable, economy minister says
Wheat production in Armenia is economically unprofitable, Minister of Economy Gevorg Papoyan told reporters outside the Armenian government...
16:46
Martin Scorsese's two film projects postponed
Martin Scorsese, the Oscar-winning filmmaker behind some of cinema’s most iconic works, had planned to begin shooting two highly...
16:34
Yerevan to host Meghraton exhibition and sale of bee products
Meghraton exhibition and sale of honey and other bee products is set to take place at Yerevan's Yeraz Park on September 28-29. The event is...
16:17
Political analyst slams Pashinian's UN speech, photo with Erdogan
Political analyst Suren Surenyants hit out at Prime Minister Nikol Pashinyan for his speech at the Summit of the Future held on the sidelines of...
15:35
UNICEF and Germany to scale up child protection services for refugee children in Armenia
UNICEF and the German Embassy in Yerevan announced a new contribution of 2,9 million Euros from the German Federal Foreign Office in the...
15:05
New COVID strain cases detected in Russia
Specialists from the Russian Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing have recorded two coronavirus...
14:35
Armenian Airlines to launch direct flights between Yerevan, Volgograd
Armenian Airlines will launch direct flights between Yerevan and Volgograd, a city in southwest Russia, starting from 1 December 2024....
14:07
Political analyst says South Caucasus turning into a 'powder keg'
Political analyst Sergei Melkonian, a research fellow at the Applied Policy Research Institute (APRI Armenia), warns that the South Caucasus...
13:45
Today marks Komitas' 155th anniversary
September 26 marks the 155th birth anniversary of Komitas Vardapet, a prominent Armenian composer, priest, musicologist, arranger, singer and...
13:30
Georgia seeks to transform South Caucasus into a region of opportunities, PM says
Georgia has led the effort to transform the South Caucasus into a region of opportunities, Georgian Prime Minister Irakli...
12:55
Pashinyan's wife chats with Turkish first lady in New York
Armenian Prime Minister Nikol Pashinyan's spouse, Anna Hakobyan, on Wednesday attended a reception in New York hosted by U.S. First Lady...
12:30
U.S. government announces $20,600,000 support to Armenia
Secretary of State Blinken and USAID Administrator Power spotlight democratic progress in Armenia and announce $20,600,000 from the United...
12:17
Blinken to meet with Armenian, Azeri FMs on Thursday evening
U.S. Secretary of State Antony Blinken’s meeting with Armenian Foreign Minister Ararat Mirzoyan and Azerbaijani Foreign Minister Jeyhun...
11:55
The government has decided to remove Mikayel Minasyan's brother from his position as minister, continuing its repressive measures
For three days, members of Armenia's ruling "Civil Contract" faction have been collecting signatures to dismiss Justice Minister...
11:35
Iran warns Israel against 'full-scale war' in Lebanon
Israel's leaders must understand their crimes won't go unpunished, Iran's foreign minister has said on the sidelines of the UN....
11:24
Armenian FM, UN refugee chief meet in New York
Armenian Foreign Minister Ararat Mirzoyan met with UN High Commissioner for Refugees Filippo Grandi on the sidelines of the 79th...
11:00
Armenia's Emma Poghosyan wins gold at World Junior Weightlifting C'ships
18-year-old Emma Poghosyan has won the first medal for Armenia at the World Junior Weightlifting Championship in Leon, Spain. Competing in...
17:04
Yerevan to host performing arts festival in October
The 22nd HIGH FEST International Performing Arts Festival will be held in Yerevan on 1-8 October. The festival is expected to bring together...
16:45
Forty days from election, Kamala Harris starts courting Armenian American voters
Democratic Presidential Candidate Kamala Harris expressed support for the “right for Armenians displaced from Nagorno-Karabakh to return...

Follow us and get updates!

Most popular articles

{"core.blocks.header.spell_message1":"Selected mistake: ","core.blocks.header.spell_message2":"Send a message about the mistake?"}