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Two gunmen have been shot dead after they opened fire outside a conference on cartoons of the Prophet Muhammad in a suburb of Dallas, the BBC reported citing US police.

A security guard was also injured. Police sealed off the Curtis Culwell Center in Garland and evacuated participants.

The gunmen's car is being searched for a possible bomb, police added.

The event, organised by a group critical of Islam, included a contest for drawings of the Prophet.

Dutch anti-Islamic politician Geert Wilders was among those attending. He tweeted that shots had been fired and he had safely left the building.

It was not clear if the shootings were related to the event, said Garland Police Department spokesman Joe Harn.

There had not been any credible threats in advance of the event, he added.

One eyewitness told the Associated Press news agency that he heard about 20 shots, which appeared to come from a car driving past the conference centre, followed by two individual shots.

The City of Garland government, in a statement on its Facebook page, said the security guard's injuries were not life-threatening.