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A car bomb claimed by Islamic State exploded in the Yemeni capital Sanaa overnight, medics said, wounding at least 28 people gathered to mourn another attack earlier this month, Reuters reported.

In a new sign that three months of war in Yemen was ratcheting up, the country's military spokesman said its forces had launched a Scud missile at a Saudi military base on Tuesday.

A Saudi-led military alliance has been bombing Yemen's dominant Houthi group and its allies in the army to dislodge them from the capital and restore the exiled president.

A sectarian-tinged conflict has raged throughout Yemen's south and center, pitting the Shi'ite Muslim Houthis against mostly Sunni local militiamen who support the Arab intervention.

The political vacuum has given hardline Sunni militants greater room to operate. They regard the Houthis as apostates worthy of death, and the overnight blast was the latest in a series of attacks on the group and their supporters.

"The explosion was caused by a car bomb which exploded behind the military hospital in the Sha'oub district in Sanaa, which injured 28 people including 12 women in a building where victims of a previous attack were being mourned," a medical source said.

In a statement posted online, Islamic State claimed responsibility for the blast, saying it had targeted the area "out of revenge for the Muslims against the Houthi apostates."