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Following years of declines in measles vaccination coverage, measles cases in 2022 have increased by 18%, and deaths have increased by 43% globally (compared to 2021). This takes the estimated number of measles cases to 9 million and deaths to 136 000 – mostly among children – according to a new report from the World Health Organization (WHO) and the U.S. Centers for Disease Control and Prevention (CDC).

Measles continues to pose a relentlessly increasing threat to children. In 2022, 37 countries experienced large or disruptive measles outbreaks compared with 22 countries in 2021. Of the countries experiencing outbreaks, 28 were in the WHO Region for Africa, six in the Eastern Mediterranean, two in the South-East Asia, and one in the European Region, WHO reported.

“The increase in measles outbreaks and deaths is staggering, but unfortunately, not unexpected given the declining vaccination rates we’ve seen in the past few years,” said John Vertefeuille, director of CDC’s Global Immunization Division. “Measles cases anywhere pose a risk to all countries and communities where people are under-vaccinated. Urgent, targeted efforts are critical to prevent measles disease and deaths.”

Measles is preventable with two doses of measles vaccine. While a modest increase in global vaccination coverage occurred in 2022 from 2021, there were still 33 million children who missed a measles vaccine dose: nearly 22 million missed their first dose and an additional 11 million missed their second dose. The global vaccine coverage rate of the first dose, at 83%, and second dose, at 74%, were still well under the 95% coverage with two doses that is necessary to protect communities from outbreaks.

Low-income countries, where the risk of death from measles is highest, continue to have the lowest vaccination rates at only 66%; a rate that shows no recovery at all from the backsliding during the pandemic. Of the 22 million children who missed their first measles vaccine dose in 2022, over half live in just 10 countries: Angola, Brazil, Democratic Republic of the Congo, Ethiopia, India, Indonesia, Madagascar, Nigeria, Pakistan and Philippines.

​​CDC and WHO urge countries to find and vaccinate all children against measles and other vaccine-preventable diseases, and encourage global stakeholders to aid countries to vaccinate their most vulnerable communities. In addition, to help prevent outbreaks, all global health partners at the global, regional, national, and local levels must invest in robust surveillance systems and outbreak response capacity to rapidly detect and respond to outbreaks.